Emergence of resistant pathogens emphasizes the need for alternatives to antimicrobial agents for acne therapy. We can compound cosmetically-appealing customized formulations which can contain numerous medications to provide a synergistic effect for treatment of resistant acne.

Int J Dermatol 1995 Jun;34(6):434-7
Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris.

Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DK
Department of Dermatology, State University of New York, College of Medicine, Brooklyn, USA.

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J Dermatol 1996 Apr;23(4):243-6
Topical spironolactone reduces sebum secretion rates in young adults.

Yamamoto A, Ito M
Department of Dermatology, Niigata University School of Medicine, Japan.

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