| We work
together with prescribers, children, and their
families to customize medications and meet specific
needs.
Children pose many challenges when it comes to
medication: they may resist having to take a medication,
dislike the taste or texture, have difficulty
swallowing solid dosage forms, and are fearful
of injections.
The limited pediatric market for most drugs may
be the leading reason for the lack of investment
in drug development for this population by the
pharmaceutical industry. Most medications are
not labeled for pediatric populations, and when
a medication is not approved for use in infants
and children, it usually is not available in a
suitable pediatric dosage form. Fortunately, our
compounding pharmacy is able to help. We can compound
oral medications into pleasantly flavored suspensions,
solutions, concentrates, freezerpops, "gummy
bears" or lozenges, in colors that entice
the child to take the medication. A palatable
formulation is more likely to improve compliance
and minimize spillage or waste during administration.
Lollipops are an ideal alternative to "swish
and swallow" medications that need to be
retained in the mouth for a prolonged period of
time. Most drugs can be compounded into transdermal
gels that can easily be applied to an appropriate
site, such as the child's wrist, for absorption
through the skin.
Professional compounding is not just diluting
existing medications, or mixing powders with bases.
We must consider physical and chemical properties
of each active and inactive ingredient in order
to prepare an effective and safe customized medication
with the desired taste, color, fragrance, viscosity,
uniformity, texture, and stability. The efficacy
of any compounded medication is influenced by
the technique and equipment used in preparing
the formulation, the purity and quality of the
ingredients, choice of vehicle (base), and proper
use of additives such as penetration enhancers. |