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Bio-Identical
vs. Non-Bio-Identical Hormones |
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| Bio-identical hormones have the
same chemical structure as hormones that are made
by the human body. The term "bio-identical"
does not indicate the source of the hormone, but
rather refers to the chemical structure. In order
for a replacement hormone to fully replicate the
function of hormones which were originally naturally
produced and present in the human body, the chemical
structure must exactly match the original. Bio-identical
hormones are able to follow normal metabolic pathways
so that essential active metabolites are formed
in response to hormone replacement therapy. |
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| There are significant differences
between hormones that are natural to humans (bio-identical)
and non-bio-identical (including horse) preparations.
Side chains can be added to a naturally-occurring
hormone to create a synthetic drug that can be patented
by a manufacturer. A patented drug can be profitable
to mass produce, and therefore a drug company can
afford to fund research as to the medication’s
use and effectiveness. However, bio-identical substances
can not be patented, so scientific studies are less
numerous on natural hormones, because medical research
is usually funded by drug companies. Structural
differences that exist between bio-identical human,
and non-bio-identical synthetic and animal hormones
may be responsible for side effects that are experienced
when non-bio-identical hormones are used for replacement
therapy. |
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| Bio-identical hormones include
estrone (E1), estradiol (E2), estriol (E3), progesterone,
testosterone, dehydroepiandrosterone (DHEA), and
pregnenolone. Our compounding specialists work together
with patients and prescribers to provide customized
bio-identical hormone replacement therapy that provides
the needed hormones in the most appropriate strength
and dosage form to meet each woman's specific needs.
Hormone replacement therapy should be initiated
carefully after a woman's medical and family history
has been reviewed. Every woman is unique and will
respond to therapy in her own way. Close monitoring
and medication adjustments are essential. |
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